Levosimendan improves cardiopulmonary resuscitation and survival by K(ATP) channel activation.

نویسندگان

  • Gianluca A A M Cammarata
  • Max Harry Weil
  • Shijie Sun
  • Lei Huang
  • Xiangshao Fang
  • Wanchun Tang
چکیده

ccurrence of severe congestive heart failure or requirement for ntra-aortic balloon pump or cardiopulmonary resuscitation (p .0081). The main and novel findings of this report are: 1) RV involveent in TLVABS is common, transient, and, when present, ortends a longer and more critical hospitalization course as ompared with patients with isolated LV involvement; and 2) RV nvolvement, when present, follows a similar pattern of regional all motion abnormalities as does LV involvement in this synrome. It is now clear that RV function is one of the most useful ndicators for patient survival in ischemic heart failure (2) and in atients with congenital heart disease (3). In our study, we show or the first time that RV involvement was common in patients ith TLVABS, with approximately one-third of patients presentng with detectable RV dysfunction on echocardiography. Even if e assume that all other five patients who did not have echocariography at initial evaluation had normal RV function, at least ne-quarter (8 of 30) of patients with TLVABS have RV involveent. The RV involvement was transient but had a significant mpact on hospitalization length and hemodynamic instability. his effect was independent from the accompanying LV dysfuncion. Clinicians should be aware of the possibility of RV dysfuncion because it might have a significant impact on patient morbidty, management, and, ultimately, outcome. The major limitation of the study lies in its retrospective nature nd relatively small number of patients. The echocardiograms were btained for clinical use and specific imaging was not performed or the assessment of RV function. In addition, although echocariography is used to assess RV function, technical limitations to maging exist because of the complexity of the RV anatomy (4). In conclusion, in TLVABS, RV involvement is relatively

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عنوان ژورنال:
  • Journal of the American College of Cardiology

دوره 47 5  شماره 

صفحات  -

تاریخ انتشار 2006